General Cell Based Assays
Dojindo Molecular Technologies Inc MitoPeDPP (50 ug x 3) is a cell-membrane-permeable probe for the detection of lipid peroxidation in mitochondria and is used in ferroptosis research (Excitation: 452 nm/Emission: 470 nm) 5 µg x 3
MitoPeDPP is a newly developed fluorescent dye that can penetrate cell membranes and is accumulated in the mitochondria due to the triphenylphosphonium moiety. MitoPeDPP accumulated in mitochondrial inner membranes is oxidized by lipophilic peroxide and then emits strong fluorescence. Since the excitation and emission wavelengths of the oxidized MitoPeDPP (Ox-MitoPeDPP) are 452 nm and 470 nm, respectively, photodamage and autofluorescence of the samples can be minimized. Therefore, MitoPeDPP can be applicable for imaging of the lipophilic peroxide in living cells under a fluorescence microscope. MitoPeDPP is used to monitor lipid peroxidation in ferroptosis research. Dojindo offers various reagents for mitochondria research. (https://www.dojindo.com/mitochondria-research/)
Eurofins Discoverx cAMP Hunter™ Human CXCL11 (CXCR3) Gi Cell-Based Assay Kit (CHO-K1)
The cAMP Hunter™ Human CXCL11 (CXCR3) Gi Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure CXCR3 (GPCR) activity via decreased levels of intracellular cAMP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human GPR75 β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human GPR75 β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure GPR75 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human IL-6 (IL6RA/IL6ST) Dimerization Cell-Based Assay Kit (U2OS)
The PathHunter Human IL-6 (IL6RA/IL6ST) Stable Cell Line Dimerization Assay (U2OS) measures ligand-induced dimerization of IL6RA/IL6ST. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Indigo Biosciences Human Aryl Hydrocarbon Receptor (AhR) All-inclusive Cell-Based Luciferase Reporter Assay Kit, 96-well assay plate format
Eliminate weeks of cell culture while achieving superior sensitivity with reproducible results from this all-inclusive cell-based luciferase reporter assay. INDIGO’s Human Aryl Hydrocarbon Receptor reporter assay allows you to quickly screen test samples to quantify functional activity, either agonist or antagonist, they may exert against AhR. Kit includes cryopreserved reporter cells engineered to provide constitutive expression of the receptor, optimized media for use during cell thawing and in diluting test samples, reference agonist, Luciferase Detection Reagent, cell culture-ready assay plate, and detailed assay protocol. INDIGO’s unique Cryomite™ process provides exceptional cell viability post-thaw and INDIGO’s strict QA process means consistent results lot to lot (product quality data available upon request). This kit allows researchers to achieve superior sensitivity, clear, reproducible results, and eliminate weeks of cell culture work.
Eurofins Discoverx PathHunter Human GPR103 β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human GPR103 β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure GPR103 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human BMP-6 (BMPR1B/BMPR2) Dimerization Cell-Based Assay Kit (U2OS)
The PathHunter Human BMP-6 (BMPR1B/BMPR2) Stable Cell Line Dimerization Assay (U2OS) measures ligand-induced dimerization of BMPR1B/BMPR2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Bioss KD-Validated Actin like 6A Rab
Actin Like 6A Primary Antibody Unconjugated Public Immunogen Range 210-274/429 Host Species Rabbit Target Species Human Mouse Rat Clonality Monoclonal Applications WB FCM IC Concentration Lot dependent Size 50 ul Storage Buffer Supplied in PBS (pH 7 4) containing 50% glycerol and 0 02% sodium azide
Sigma Aldrich Fine Chemicals Biosciences Mitochondrial Membrane Pot
Mitochondria generate a potential across their membranes due to the activities of enzymes of the electron transport chain. During apoptosis collapse of the mitochondrial membrane potential (MMP) coincides with the opening of the mitochondrial permeability transition pores leading to the release of cytochrome c into the cytosol which in turn triggers other downstream events in the apoptotic cascade.
Eurofins Discoverx PathHunter eXpress OPRL1 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0264E2CP0M)
The PathHunter OPRL1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. orphanin FQ) based activation of OPRL1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged OPRL1 and EA-tagged β-Arrestin-2. Activation of OPRL1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter Human IL-33 (IL1RL1/IL1RAP) Dimerization Cell-Based Assay Kit (U2OS)
The PathHunter Human IL-33 (IL1RL1/IL1RAP) Stable Cell Line Dimerization Assay (U2OS) measures ligand-induced dimerization of IL1RL1/IL1RAP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
American Research Products Inc Mouse FMS like tyrosine kinase
Mouse FMS-like tyrosine kinase 3 ligand Flt-3L ELISA Kit from CUSABIO Detection Range 15 6 pg/mL-1000 pg/mL Sensitivity 3 9 pg/mL Sample serum plasma tissue homogenates Method Sandwich
Eurofins Discoverx PathHunter Human FOXO3 Nuclear Translocation Cell-Based Assay Kit (U2OS)
The PathHunter Human FOXO3 Stable Cell Line Nuclear Translocation Assay (U2OS) contains a stable clonal cell line used to measure PI3K pathway activation via nuclear translocation of FOXO3. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Cayman Chemical 8pIpRIdIno NAD sodIM sal 700ug
A derivative of NAD+; has been used in the determination of PARP target proteins; a synthetic intermediate in the synthesis of cADPR derivatives
Arbor Assays Glutathione Fluorescent Detection Kit (5 Plate)
The DetectX Glutathione (GSH) Fluorescent Detection Kit utilizes a proprietary non-fluorescent molecule, ThioStar, that covalently binds to the free thiol group on GSH to yield a highly fluorescent product.